Saturday, 14 January 2012

Alternative to regular maxalon for morning sickness in pregnancy

as the title implies there are an alternative to the regular maxalon that local clinics and hospital provide.
another aid for morning sickness and hyperemesis in pregnancy is veloxin




Information

Active ingredients : meclozine hydrochloride 25mg
                                pyridoxine hydrochloride 50mg

Indication              : for prevention and treatment of nausea, vomiting or vertigo

Dosage                  : 1-2 tablets daily ( adult )

contraindication    : known hypersensitivity to meclozine or/and pyridoxine, lactation

use in pregnancy   : meclozine classified by FDA as category B, there are no adequate and well          controlled studies in pregnant women or animal studies which have shown adverse effect. this means its not expected to harm an unborn baby. pyridoxine is classified as category A by FDA therefore its considered safe for pregnancy

side effects            : drowsiness, dry mouth, headache and gastrointestinal tract disturbances and rarely blurred vision

Hyperemesis gravidarum

Hyperemesis gravidarum or simply pregnancy induced vomitting/nausea is a condition that usually happened during the 1st trimester of pregnancy (often around 8 - 12 weeks of gestation).


causes are unknown, leading explanation ranging from raised levels of beta HCG (human chorionic gonadotrophin) to increased level of estrogen leading to nausea and regurgitation of stomach acids in some women.

symptoms include loss of weight, dehydration, metabolites imbalance and nutritional deficiency and in severe cases might lead to acute renal failure and may cause baby to have SGA ( small for gestation age) or LBW (low birth weight)

diagnosis are often made base on clinical symptoms reflecting the degree of dehydration and followed by a urine test on ketone levels mirroring the degree of dehydration

treatment are divided to outpatient and inpatient and are justified by clinical symptoms, physical examination findings and laboratory investigation result.

for outpatient treatment its normally given anti emetics e.g. tablets maxalon 10 mg tds/prn and advices

for inpatient treatment its based on the severity of symptoms, degree of dehydration and with urine ketone level of 2+ and above will be warranted for admission. patient will usually be given 6 pints of fluids per 24 hour with intravenous anti emetics

criteria for discharge will be depending on urine ketone level and overall patient well being.